BRIDGED BICYCLIC NUCLEOSIDES

摘要

The present invention relates to 2′-C-Bridged Bicyclic Nucleosides and Nucleotides, and oligonucleotides comprising at least one 2′-C-Bridged Bicyclic Nucleotides. The present invention further provides pharmaceutical compositions comprising the nucleosides, nucleotides, and oligonucleotides, as well as their respective methods of use and synthesis.

主权项

1. An oligonucleotide comprising at least one 2′-C-Bridged Bicyclic Nucleotide.