发明名称 USE OF TRANSCRANIAL MAGNETIC STIMULATION TO MODULATE PERMEABILITY OF THE BLOOD-BRAIN BARRIER
摘要 Transcranial magnetic stimulation (TMS) is used to modulate permeability of the blood brain barrier in a transient, safe and non-invasive manner. A conventional or deep TMS coil may be placed on a head in a vicinity of a tumor, for example. A series of magnetic pulses is provided to the brain with a tailored stimulation protocol. In one of many possible clinical applications, a pharmaceutical substance may be introduced during a time frame before, during or after providing the magnetic pulses to treat a tumor in the brain.
申请公布号 US2016008619(A1) 申请公布日期 2016.01.14
申请号 US201314378427 申请日期 2013.02.13
申请人 BRAINSWAY, LTD. 发明人 PELL GABY;ZANGEN ABRAHAM;ROTH YIFTACH
分类号 A61N2/00;A61N2/02 主分类号 A61N2/00
代理机构 代理人
主权项 1. A method for modulating permeability of the blood brain barrier, the method comprising: providing a system for transcranial magnetic stimulation; placing said system on a scalp; and providing a series of magnetic pulses to the brain via the system, said providing done in a range of at least 0.2 Hz stimulation frequency, at least 80% of resting motor threshold stimulation amplitude, and at least 100 stimulation pulses.
地址 JERUSALEM IL