| 发明名称 |
TARGETING GLUTAMINE METABOLISM IN BRAIN TUMORS |
| 摘要 |
The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for diagnosing and treating MYC-driven tumors. In one embodiment, a method for treating a cancer associated with MYC in a patient comprises the step of administering a glutamine metabolism inhibitor to the patient. In specific embodiments, the cancer associated with MYC is medulloblastoma, glioblastoma or a primitive neuroectodermal tumor. |
| 申请公布号 |
US2016008380(A1) |
申请公布日期 |
2016.01.14 |
| 申请号 |
US201414772837 |
申请日期 |
2014.03.06 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
Raabe Eric H.;Hanaford Allison;Ahsan Sama;Taylor Isabella;Eberhart Charles |
| 分类号 |
A61K31/655;G01N33/574;A61K31/42 |
主分类号 |
A61K31/655 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for treating a cancer associated with MYC in a patient comprising the step of administering a glutamine metabolism inhibitor to the patient. |
| 地址 |
Baltimore MD US |
