摘要 |
PROBLEM TO BE SOLVED: To provide silicone pressure sensitive adhesives that: are used in transdermal drug delivery, wound dressings, scar dressings, and other healthcare applications; are biocompatible, gentle on the skin, and securely attach medical devices to the body when the environment is dry; and does not lose their adhesion to skin under moist conditions such as during skin perspiration.SOLUTION: Silicone pressure sensitive adhesive compositions include amphiphilic copolymers. The amphiphilic copolymers are prepared using at least one reactive hydrophilic or amphiphilic monomer, oligomer, macromer, and a combination thereof based on a polydimethylhydrogensiloxane or polydimethylsiloxane-based macroinitiator. The pressure sensitive adhesive comprises poly(dimethylsiloxane)-poly(maleic anhydride-vinyl ethyl ether) (PDMS/MA/VEE). |