发明名称 N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS
摘要 PROBLEM TO BE SOLVED: To provide new LpxC inhibitors, more specifically, methods of using them for treating bacterial infections and pharmaceutical compositions containing such compounds.SOLUTION: The present invention is directed to hydroxamic acid derivatives represented by formula (I), or pharmaceutically acceptable salts thereof. (Ris C1-3 alkyl; Ris H or C1-3 alkyl; Ris H, halogen, C1-3 alkyl, trifluoromethyl or the like; L is absent, or alkylene, alkenylene or the like; D is cycloalkyl, aryl or the like; T is (CH), S-(CH)-O-(CH)or the like; and G is absent, or cycloalkyl or the like.)
申请公布号 JP2016006064(A) 申请公布日期 2016.01.14
申请号 JP20150142292 申请日期 2015.07.16
申请人 PFIZER INC 发明人 MATTHEW FRANK BROWN;CHE YE;MARFAT ANTHONY;MICHAEL JOSEPH MELNICK;JUSTIN IAN MONTGOMERY;USA REILLY
分类号 C07D213/64;A61K31/4412;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/506;A61P31/04;C07D213/643;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D405/04;C07D405/10;C07D413/10 主分类号 C07D213/64
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