摘要 |
PROBLEM TO BE SOLVED: To provide new LpxC inhibitors, more specifically, methods of using them for treating bacterial infections and pharmaceutical compositions containing such compounds.SOLUTION: The present invention is directed to hydroxamic acid derivatives represented by formula (I), or pharmaceutically acceptable salts thereof. (Ris C1-3 alkyl; Ris H or C1-3 alkyl; Ris H, halogen, C1-3 alkyl, trifluoromethyl or the like; L is absent, or alkylene, alkenylene or the like; D is cycloalkyl, aryl or the like; T is (CH), S-(CH)-O-(CH)or the like; and G is absent, or cycloalkyl or the like.) |