| 发明名称 |
SE33 MUTATIONS IMPACTING GENOTYPE CONCORDANCE |
| 摘要 |
Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification. |
| 申请公布号 |
US2016010146(A1) |
申请公布日期 |
2016.01.14 |
| 申请号 |
US201514809418 |
申请日期 |
2015.07.27 |
| 申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
GREEN Robert;Wang Dennis;Mulero Julio;Lagace Robert |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleic acid composition comprising a single nucleotide polymorphism (SNP), wherein said SNP is located at one of positions 316, 317 or 324 as illustrated in SEQ ID NO:3, and wherein said SNP is 3′ of the short tandem repeat (STR) region of the SE33 locus. |
| 地址 |
Carlsbad CA US |
