| 发明名称 |
PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM |
| 摘要 |
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels. |
| 申请公布号 |
US2016009748(A1) |
申请公布日期 |
2016.01.14 |
| 申请号 |
US201514817690 |
申请日期 |
2015.08.04 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN ;EASTERN MICHIGAN UNIVERSITY |
发明人 |
Lawrence Daniel A.;Emal Cory;Cale Jacqueline;Su Enming Joe;Warnock Mark;Li Shih-Hon;Cupp Jeanne Ann |
| 分类号 |
C07H15/203;A61K38/17;A61K38/48;C07C69/94;A61K31/235;C07C271/22;A61K31/27;C07C311/29;A61K31/18;C07C235/68;A61K31/166;C07D213/82;A61K31/444;C07D295/192;A61K31/495;C07C311/49;C07D295/26;A61K31/50;A61K31/5375;A61K31/7034 |
主分类号 |
C07H15/203 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
Ann Arbor MI US |
