| 发明名称 |
Methods for Achieving Therapeutically Effective Doses of anti-CD47 Agents |
| 摘要 |
Methods are provided for treating a subject with a therapeutic dose of anti-CD47 agent by administering a primer agent prior to administering a therapeutically effective dose of an anti-CD47 agent to the subject. |
| 申请公布号 |
US2016008429(A1) |
申请公布日期 |
2016.01.14 |
| 申请号 |
US201414769069 |
申请日期 |
2014.02.26 |
| 申请人 |
The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Willingham Stephen;Howard Maureen;Liu Jie;Majeti Ravindra;Prohaska Susan Sweeney;Volkmer Anne Kathrin;Volkmer Jens-Peter;Weissman Irving L. |
| 分类号 |
A61K38/18;C07K16/28;A61K39/395 |
主分类号 |
A61K38/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a subject with a therapeutic dose of anti-CD47 agent, the method comprising:
(a) administering a first primer agent to the subject; and (b) administering a therapeutically effective dose of an anti-CD47 agent to the subject, wherein step (b) is after at least about 3 days after beginning step (a). |
| 地址 |
Standford CA US |
