Methods And Materials For Microorganism Capture

摘要

Material complexes that capture biologicals and methods of synthesizing and using such complexes composed of fluid-insoluble material and a receptor are provided herewith. The fluid-insoluble material has reactive functionality on its surface, including hydroxyl, amino, mercapto or epoxy functionality material. The material can be agarose, sand, textile, or any combination thereof. The receptor is selected from the group consisting of mono- and poly-saccharides, heparin, or any combination thereof. Also provided are methods whereby releasing the captured biologicals is controllable.

主权项

1. A method for immobilizing a biological comprising:
mixing a fluid sample comprising the biological through a material complex comprising a hydroxyl-, amino-, mercapto or epoxy-containing material that is fluid-insoluble and at least one receptor selected from lactose, lactose derivative, mono- or poly-saccharide, heparin, chitosan, or any combination thereof, wherein the receptor is bound to the material; and separating the biological from the sample by adsorbing the biological to the material complex.