DELIVERY SYSTEM COMPRISING SILICON-CONTAINING MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide a composition comprising nanoparticles of a hydrolysable silicon-containing material for use as a delivery system for a bioactive ingredient.SOLUTION: The composition comprising nanoparticles of a hydrolysable silicon-containing material for use as a delivery system for a bioactive ingredient is provided in which the surface of the silicon-containing material is associated with a stabilizing agent which modifies the rate of hydrolysis of the silicon-containing material and/or inhibits the rate of orthosilicic acid polymerization. A method of promoting a controlled release of orthosilicic acid on degradation of the composition comprising nanoparticles of a hydrolysable silicon-containing material is also provided which involves the treatment of the surface of the silicon-containing material with a stabilizing agent to modify the rate of hydrolysis of the silicon-containing material and/or inhibit the rate of orthosilicic acid polymerization.