| 发明名称 |
POLY(LACTIC-CO-GLYCOLIC ACID (PLGA) COMPOSITES WITH MAGNESIUM WIRES ENHANCED NETWORKING OF PRIMARY NEURONS |
| 摘要 |
A bioresorbable material incorporating magnesium (Mg) wires into NGCs is disclosed. The bioresorbable material includes magnesium, and a biodegradable polymer, for example, poly(lactic-co-glycolic acid (PLGA). The bioresorbable material can include magnesium wires incorporated into a poly(lactic-co-glycolic acid (PLGA) scaffold to provide both directional and biological cues in a fully bioresorbable material. A method of producing a bioresorbable material is also disclosed, which includes placing a plurality of magnesium (Mg) wires on a layer of a poly(lactic-co-glycolic acid (PLGA) solution, placing a second layer of the poly(lactic-co-glycolic acid (PLGA) solution on the plurality of magnesium (Mg) wires, and drying the plurality of magnesium (Mg) wires between the two layers of poly(lactic-co-glycolic acid (PLGA) solution. |
| 申请公布号 |
US2016008516(A1) |
申请公布日期 |
2016.01.14 |
| 申请号 |
US201514688774 |
申请日期 |
2015.04.16 |
| 申请人 |
The Regents of the University of California |
发明人 |
LIU Huinan;AUGELLO Catherine;ZAHEDI Atena;ETHELL Iryna |
| 分类号 |
A61L27/48;A61L27/58;A61L27/18;B29C35/02;B29C70/70;B29C33/14;B29C33/42;A61L27/54;B29C70/88 |
主分类号 |
A61L27/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bioresorbable material, comprising:
magnesium; and a biodegradable polymer. |
| 地址 |
Oakland CA US |
