发明名称 |
4- (P-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES |
摘要 |
The present invention provides specific 4-(p-quinonyl)-2-hydroxybutanamide derivative compounds, pharmaceutical compositions comprising them, and those compounds and compositions for use methods of treating or suppressing a mitochondrial disorder, modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, and treating a subject suffering from a pervasive developmental disorder selected from the group consisting of Autistic Disorder, Asperger's Disorder, Childhood Disintegrative Disorder (CDD), Rett's Disorder, and Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS). |
申请公布号 |
EP2220030(B1) |
申请公布日期 |
2016.01.13 |
申请号 |
EP20080847883 |
申请日期 |
2008.11.04 |
申请人 |
EDISON PHARMACEUTICALS, INC. |
发明人 |
JANKOWSKI, ORION, D.;WESSON, KIERON, E.;MOLLARD, PAUL;SHRADER, WILLIAM, D. |
分类号 |
C07C235/78;A61K31/16;A61K31/445;A61P25/00;A61P25/16;C07C317/28;C07D207/27;C07D213/40;C07D223/04;C07D233/61;C07D295/02;C07D295/185;C07D295/192;C07D295/24;C07D307/14 |
主分类号 |
C07C235/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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