发明名称 |
Immunogenic compositions comprising a gp120 related polypeptide |
摘要 |
The present invention relates to particular immunogenic compositions comprising a gpl2O related polypeptide and an adjuvant, wherein the adjuvant comprises a saponin and a lipopolysaccharide. Such compositions are substantially free of a NefTat related polypeptide, comprise between 1O-4Oug of a lipopolysaccharide and between 1O-4Oug of an immunologically active saponin fraction derived from the bark of Quillaja Saponaria Molina presented in the form of a liposome or have a concentration of sodium chloride of 130 mM or lower. |
申请公布号 |
IE86613(B1) |
申请公布日期 |
2016.01.13 |
申请号 |
IE20130000343 |
申请日期 |
2013.11.08 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
PATRICIA B. BOURGUIGNON;MARGUERITE CHRISTINE KOUTSOUKOS;CLARISSE MARIE-MADELEINE LORIN |
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