Device for administering therapeutic substances using a high velocity liquid-gas stream

摘要

A device, system and method for treatment of tissue by direct application thereto of therapeutic substances in the form of a stream of therapeutic droplets carried in a high velocity gas. The high velocity gas is produced by accelerating a flow of gas through at least one gas discharge nozzle. At least one flow of therapeutic liquid is introduced into the high velocity gas through at least one liquid discharge nozzle, thereby fragmenting the at least one flow of therapeutic liquid into a stream of therapeutic droplets. The stream is accelerated to a velocity similar to the velocity of the gas discharge flow. The accelerated therapeutic droplet stream is then applied to a tissue mass for therapeutic treatment. The therapeutic substances are provided by containers mounted directly on the device. The containers contain predefined dosages and/or concentrations of the therapeutic substances.

主权项

1. A device for administering a therapeutic substance to tissue for use with a pressurized gas source, and comprising:
a) a housing having a liquid inlet port; b) a gas inlet port connected to the pressurized gas source; c) at least one therapeutic substance supply assembly mounted onto said housing, each therapeutic substance supply assembly comprising at least one container connector configured for receiving a container containing a predefined quantity or concentration of a liquid therapeutic substance, each container in fluid flow communication with one of at least one valve projecting from and external to said assembly, each of said at least one valve is associated with a different container and user operable between an open and a closed position, said at least one valve is adapted for control of a continuous flow of said at least one liquid therapeutic substance during operation of said device; and d) a stream jet delivery nozzle arrangement in fluid flow communication with said gas inlet port and in fluid flow communication with said therapeutic substance supply assembly,
the liquid therapeutic substance being discharged from said stream jet delivery nozzle arrangement into an elevated velocity flow of gas discharged from said delivery nozzle arrangement,wherein the liquid therapeutic substance is brought from an assembly base of said therapeutic substance supply assembly to said liquid inlet port through a flexible tube positioned external to said housing which directly connects said assembly base to said liquid inlet port.