| 发明名称 |
Oligomer-opioid agonist conjugates |
| 摘要 |
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer. |
| 申请公布号 |
US9233168(B2) |
申请公布日期 |
2016.01.12 |
| 申请号 |
US201414581832 |
申请日期 |
2014.12.23 |
| 申请人 |
Nektar Therapeutics |
发明人 |
Riggs-Sauthier Jennifer;Deng Bo-Liang;Riley Timothy A. |
| 分类号 |
A61K31/485;C07D489/04;A61K47/48;A61K31/439;C07D489/02;A61K31/402;A61K31/4025;A61K31/4468 |
主分类号 |
A61K31/485 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound according to the following Formula:and enantiomeric and pharmaceutically acceptable salt forms thereof, wherein n is an integer from 1 to 30. |
| 地址 |
San Francisco CA US |
