| 发明名称 |
Interfering RNA delivery system and uses thereof |
| 摘要 |
The invention provides a delivery system comprising a cell penetrating peptide, a polyarginine peptide, and an interfering RNA molecule. The system can be used for delivering interfering RNA molecules into a cell in vivo or in vitro. Therapeutic uses for the delivery system are also provided. |
| 申请公布号 |
US9233170(B2) |
申请公布日期 |
2016.01.12 |
| 申请号 |
US201414158179 |
申请日期 |
2014.01.17 |
| 申请人 |
Arrowhead Research Corporation |
发明人 |
Chatterton Jon E. |
| 分类号 |
C12N15/11;A61K47/48 |
主分类号 |
C12N15/11 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An interfering RNA delivery system comprising an interfering RNA molecule linked to a cell penetrating peptide (CPP)-Arg peptide wherein the CPP-Arg peptide comprises the sequence as set forth in SEQ ID NO: 3. |
| 地址 |
Pasadena CA US |
