发明名称 Prognostic signature for colorectal cancer recurrence
摘要 An assay system is useful for predicting recurrence and/or non-recurrence of colorectal cancer in a patient. The assay system is adapted to analyze a patient sample for quantitative expression of a prognostic genetic profile correlated with colorectal cancer recurrence. The profile includes the expression of the nucleic acid sequences of SEQ ID NOS: 1, 2, 3, 4, and 5.
申请公布号 US9234245(B2) 申请公布日期 2016.01.12
申请号 US201213351485 申请日期 2012.01.17
申请人 Everist Genomics, Inc. 发明人 Worzel William P.;Lenehan Peter F.;Almal Arpit;Fry David W.
分类号 C07H21/04;C07H21/02;C12Q1/68 主分类号 C07H21/04
代理机构 Dykema Gossett PLLC 代理人 Dykema Gossett PLLC
主权项 1. A kit or assay system for determining risk of colorectal cancer recurrence, the kit or assay system consisting of a set of cDNA molecules, wherein the set of cDNA molecules consists of: (i) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 1; (ii) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 2; (iii) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 3; (iv) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 4; and (v) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 5.
地址 Ann Arbor MI US