发明名称 |
Prognostic signature for colorectal cancer recurrence |
摘要 |
An assay system is useful for predicting recurrence and/or non-recurrence of colorectal cancer in a patient. The assay system is adapted to analyze a patient sample for quantitative expression of a prognostic genetic profile correlated with colorectal cancer recurrence. The profile includes the expression of the nucleic acid sequences of SEQ ID NOS: 1, 2, 3, 4, and 5. |
申请公布号 |
US9234245(B2) |
申请公布日期 |
2016.01.12 |
申请号 |
US201213351485 |
申请日期 |
2012.01.17 |
申请人 |
Everist Genomics, Inc. |
发明人 |
Worzel William P.;Lenehan Peter F.;Almal Arpit;Fry David W. |
分类号 |
C07H21/04;C07H21/02;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
Dykema Gossett PLLC |
代理人 |
Dykema Gossett PLLC |
主权项 |
1. A kit or assay system for determining risk of colorectal cancer recurrence, the kit or assay system consisting of a set of cDNA molecules, wherein the set of cDNA molecules consists of:
(i) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 1; (ii) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 2; (iii) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 3; (iv) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 4; and (v) a cDNA molecule consisting of the nucleotide sequence of SEQ ID NO: 5. |
地址 |
Ann Arbor MI US |