| 发明名称 | Creating bioengineered lymph nodes | ||
| 摘要 | The invention provides compositions and methods of treating various conditions, including tumors, with compositions comprising dendritic cells expressing exogenous chemokines. | ||
| 申请公布号 | US9234175(B2) | 申请公布日期 | 2016.01.12 |
| 申请号 | US201013508305 | 申请日期 | 2010.11.16 |
| 申请人 | H. Lee Moffitt Cancer Center and Research Institute, Inc. | 发明人 | Mule James J. |
| 分类号 | C12N5/071;C12N15/86;C12N15/74;C12N15/87;C12N5/0784;C07K14/52;A61K35/12 | 主分类号 | C12N5/071 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A composition comprising an isolated, engineered dendritic cell comprising exogenous cDNAs encoding exogenous Chemokine (C—C Motif) Ligand (CCL) 8 (CCL-8), CCL-18, and C—X—C Motif Chemokine 13 (CXCL-13). | ||
| 地址 | Tampa FL US | ||