发明名称 Repair and regeneration of ocular tissue using postpartum-derived cells
摘要 Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
申请公布号 US9234172(B2) 申请公布日期 2016.01.12
申请号 US201414444689 申请日期 2014.07.28
申请人 DePuy Synthes Products, Inc. 发明人 Mistry Sanjay;Messina Darin
分类号 C12N5/079;C12N5/073;C12N5/074;A61K35/12 主分类号 C12N5/079
代理机构 Johnson & Johnson 代理人 Plantz Bernard F.;Johnson & Johnson
主权项 1. A method of inducing differentiation of neural progenitor cells comprising co-culturing neural progenitor cells with isolated umbilicus-derived cells isolated from human umbilical cord tissue substantially free of blood, wherein the co-culturing induces the differentiation of the neural progenitor cells, and wherein the isolated umbilicus cells are capable of self-renewal and expansion in culture, have the potential to differentiate into cells of at least a neural phenotype, maintain a normal karyotype upon passaging and lack production of CD117.
地址 Raynham MA US