发明名称 |
Repair and regeneration of ocular tissue using postpartum-derived cells |
摘要 |
Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed. |
申请公布号 |
US9234172(B2) |
申请公布日期 |
2016.01.12 |
申请号 |
US201414444689 |
申请日期 |
2014.07.28 |
申请人 |
DePuy Synthes Products, Inc. |
发明人 |
Mistry Sanjay;Messina Darin |
分类号 |
C12N5/079;C12N5/073;C12N5/074;A61K35/12 |
主分类号 |
C12N5/079 |
代理机构 |
Johnson & Johnson |
代理人 |
Plantz Bernard F.;Johnson & Johnson |
主权项 |
1. A method of inducing differentiation of neural progenitor cells comprising co-culturing neural progenitor cells with isolated umbilicus-derived cells isolated from human umbilical cord tissue substantially free of blood, wherein the co-culturing induces the differentiation of the neural progenitor cells, and wherein the isolated umbilicus cells are capable of self-renewal and expansion in culture, have the potential to differentiate into cells of at least a neural phenotype, maintain a normal karyotype upon passaging and lack production of CD117. |
地址 |
Raynham MA US |