发明名称 |
Compositions and methods for the treatment of VprBP-related cancers |
摘要 |
This disclosure provides methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity. Also provided are methods of determining the effectiveness of the methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity, methods for detecting a cancer, and methods for screening potential agents that inhibit VprBP kinase activity. |
申请公布号 |
US9234018(B2) |
申请公布日期 |
2016.01.12 |
申请号 |
US201414514223 |
申请日期 |
2014.10.14 |
申请人 |
University of Southern California |
发明人 |
An Woojin;Neamati Nouri;Kim Kyunghwan;Lu Wange |
分类号 |
A61K38/00;C07D495/04;C07K14/47;C07K7/06;C07K7/08;C12N15/113;G01N33/50;C12Q1/48;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
Foley & Lardner LLP |
代理人 |
Foley & Lardner LLP ;Konski Antoinette F. |
主权项 |
1. A compound of the formula: or a pharmaceutically acceptable salt or a solvate thereof. |
地址 |
Los Angeles CA US |