发明名称 Hepcidin inhibitors for regulating iron homeostasis
摘要 The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders resulting from iron overload while inhibitors of hepcidin can be used in the treatment of anemia.
申请公布号 US9234903(B2) 申请公布日期 2016.01.12
申请号 US200611602402 申请日期 2006.11.21
申请人 INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE 发明人 Nicolas Gaël;Vaulont Sophie;Kahn Axel
分类号 G01N33/90;A61K38/17 主分类号 G01N33/90
代理机构 Marshall, Gerstein & Borun LLP 代理人 Marshall, Gerstein & Borun LLP
主权项 1. A pharmaceutical composition for parenteral administration comprising (a) an antibody that binds a human hepcidin peptide comprising the amino acid sequence set forth in SEQ ID NO: 3 and that is capable of inhibiting the activity of hepcidin and (b) a suitable carrier or excipient, wherein the composition is for administration by intramuscular, subcutaneous, intravenous or intraperitoneal injection.
地址 Paris FR