| 发明名称 | Methods for treating depression using NCAM peptide mimetics | ||
| 摘要 | The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness. | ||
| 申请公布号 | US9234242(B2) | 申请公布日期 | 2016.01.12 |
| 申请号 | US201213431893 | 申请日期 | 2012.03.27 |
| 申请人 | THE BOARD OF THE TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 发明人 | Akil Huda;Watson Stanley J.;Turner Cortney;Bunny William E.;Jones Edward G.;Myers Richard M.;Schatzberg Alan F. |
| 分类号 | A61K38/10;A61K38/18;C12Q1/68;A61K38/17;G01N33/50;A61K38/03 | 主分类号 | A61K38/10 |
| 代理机构 | Kilpatrick Townsend & Stockton LLP | 代理人 | Kilpatrick Townsend & Stockton LLP |
| 主权项 | 1. A method for treating a major depressive disorder (MDD) in a subject, the method comprising administering a therapeutically effective amount of a ligand comprising an FG loop (FGL) peptide derived from NCAM to the subject, wherein the ligand activates fibroblast growth factor (FGF) receptor and is an NCAM peptide mimetic. | ||
| 地址 | Palo Alto CA US | ||