发明名称 Chlorotoxin polypeptides and conjugates and uses thereof
摘要 Reduced lysine chlorotoxin polypeptides that may be used to generate single species conjugates of chlorotoxin. Conjugates comprising such chlorotoxin polypeptides and pharmaceutical compositions thereof. Methods of using such compositions and/or conjugates.
申请公布号 US9234015(B2) 申请公布日期 2016.01.12
申请号 US201414450182 申请日期 2014.08.01
申请人 Morphotek, Inc. 发明人 Sentissi Abdellah;Jacoby Douglas B.
分类号 A61K38/00;C07K14/435;A61K47/48;C07K14/00;A61K31/337;A61K51/08 主分类号 A61K38/00
代理机构 Choate Hall & Stewart LLP 代理人 Jarrell Brenda Herschbach;Choate Hall & Stewart LLP
主权项 1. A polypeptide comprising an amino acid sequence having at least 90% sequence identity with SEQ ID NO:1 and comprising no more than one lysine residue.
地址 Exton PA US