发明名称 |
Chlorotoxin polypeptides and conjugates and uses thereof |
摘要 |
Reduced lysine chlorotoxin polypeptides that may be used to generate single species conjugates of chlorotoxin. Conjugates comprising such chlorotoxin polypeptides and pharmaceutical compositions thereof. Methods of using such compositions and/or conjugates. |
申请公布号 |
US9234015(B2) |
申请公布日期 |
2016.01.12 |
申请号 |
US201414450182 |
申请日期 |
2014.08.01 |
申请人 |
Morphotek, Inc. |
发明人 |
Sentissi Abdellah;Jacoby Douglas B. |
分类号 |
A61K38/00;C07K14/435;A61K47/48;C07K14/00;A61K31/337;A61K51/08 |
主分类号 |
A61K38/00 |
代理机构 |
Choate Hall & Stewart LLP |
代理人 |
Jarrell Brenda Herschbach;Choate Hall & Stewart LLP |
主权项 |
1. A polypeptide comprising an amino acid sequence having at least 90% sequence identity with SEQ ID NO:1 and comprising no more than one lysine residue. |
地址 |
Exton PA US |