发明名称 TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS
摘要 Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease.
申请公布号 PH12015502002(A1) 申请公布日期 2016.01.11
申请号 PH2002120155020 申请日期 2015.09.08
申请人 ONYX THERAPEUTICS, INC. 发明人 MCMINN, DUSTIN;JOHNSON, HENRY;BOWERS, SIMEON;MOEBIUS, DAVID, C
分类号 A61K31/336;A61K31/404;C07D303/32;C07D405/12;C07D409/12 主分类号 A61K31/336
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