发明名称 |
TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS |
摘要 |
Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease. |
申请公布号 |
PH12015502002(A1) |
申请公布日期 |
2016.01.11 |
申请号 |
PH2002120155020 |
申请日期 |
2015.09.08 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
MCMINN, DUSTIN;JOHNSON, HENRY;BOWERS, SIMEON;MOEBIUS, DAVID, C |
分类号 |
A61K31/336;A61K31/404;C07D303/32;C07D405/12;C07D409/12 |
主分类号 |
A61K31/336 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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