摘要 |
<p>The invention relates to a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomersthereof and/or solvates thereof: in which: •R2, R3, R4, R5, and R7 independently represent: a hydrogen or halogen atom; a C1-C4 alkyl radical; a C1-C4 hydroxyalkyl radical; a carboxyl radical; a (C1-C4)alkoxycarbonyl radical; • R1 and R6, which may be identical or different, represent: hydrogen atom; C1-C10 and preferably Ci-C6 alkyl radical, - optionally interrupted with one or more heteroatoms chosen from O and S or with one or more groups -NR and/or - optionally terminating with at least one group -NX1X2 or at least one group -OX3, • X1 and X2 independently denote - a hydrogen atom, a linear C1-C6 alkyl radical, a branched C3-C6 alkyl radical, a linear C1-C6 hydroxyalkyl radical or a branched C3-C6 hydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; the said heterocycle possibly being substituted with one or more linear or branched C1-C4 alkyl or C1-C4 hydroxyalkyl radicals, • X3 denotes - a hydrogen atom - a linear C1-C4 or branched C3-C4 alkyl radical, and • R denotes - a hydrogen atom - a linear C1-C4 alkyl radical.</p> |