发明名称 |
TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES BY THE SUE OF CR2-FH MOLECULES CR2-FH H |
摘要 |
<p>The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.</p> |
申请公布号 |
HK1206368(A1) |
申请公布日期 |
2016.01.08 |
申请号 |
HK20150106966 |
申请日期 |
2015.07.21 |
申请人 |
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT |
发明人 |
GILKESON, GARY;TOMLINSON, STEPHEN;HOLERS, MICHAEL;ROHRER, BAERBEL |
分类号 |
C07K;A61K |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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