| 发明名称 |
BIODOSIMETRY PANELS AND METHODS |
| 摘要 |
The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure. |
| 申请公布号 |
US2016003822(A1) |
申请公布日期 |
2016.01.07 |
| 申请号 |
US201514854514 |
申请日期 |
2015.09.15 |
| 申请人 |
Meso Scale Technologies, LLC ;The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. |
发明人 |
Blakely William F.;Glezer Eli N.;Kenten John;Kumar Sudeep;Mathew Anu;Ossetrova Natalia I.;Sigal George |
| 分类号 |
G01N33/569;G01N33/68 |
主分类号 |
G01N33/569 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of assaying peripheral blood leukocyte status in a sample comprising
(a) measuring a level of a plurality of hematology surrogate biomarkers in a sample, said plurality of biomarkers comprises a lymphocyte cell surface marker, a neutrophil cell surface marker, and combinations thereof; (b) comparing said level of said biomarkers in said sample to a level of said biomarkers in a normal control sample; and (c) determining said peripheral blood leukocyte status based on said comparison step (b). |
| 地址 |
Rockville MD US |
