METHODS FOR CLASSIFYING A CANCER AS SUSCEPTIBLE TO TMEPAI-DIRECTED THERAPIES AND TREATING SUCH CANCERS

摘要

The invention provides methods for classifying a cancer as susceptible to transmembrane prostate androgen induced (TMEPAI)-directed therapies, and methods for treating such cancers. The field of the invention pertains generally to medicine, pathology and oncology. More particularly, it addresses the treatment of breast cancer, such as triple-negative breast cancer, using a transmembrane prostate androgen induced (TMEPAI)-directed therapy.

主权项

1. A method of inhibiting a cancer cell that overexpresses transmembrane prostate androgen induced (TMEPAI) compared to normal control cell comprising contacting the cancer cell with an agent that inhibits TMEPAI expression or activity.