MULTIPLE ION GATE METHOD AND APPARATUS

摘要

A second gate in an Ion Mobility Spectrometer is used to select or block different time windows of the ion mobility spectrum. A second gate in the Ion Mobility Mass Spectrometer is used to modulate peak intensities in the IMS spectrum, allowing each peak in the IMS spectrum to be unambiguously matched with its set of fragment ions in a subsequent MS-MS mass spectrum.

主权项

1. A method for operating a ion mobility spectrometer, comprising:
(a) Opening a first ion gate to allow a packet of mixed ions into the ion mobility analyzer, (b) Separating ions in the ion mobility analyzer, (c) Opening a second gate multiple times according to a waveform consisting of a series of time windows to allow ions with certain ion mobilities to pass through the second gate and block the ions with other ion mobilities.