发明名称 METHOD TO IDENTIFY BACTERIAL SPECIES BY MEANS OF GAS CHROMATOGRAPHY/MASS SPECTROMETRY IN BIOLOGICAL SAMPLES
摘要 Method to identify bacterial classes in a biological sample, in particular a urine sample, that provides to carry out an analysis by means of Gas Chromatography-Mass Spectrometry (GC/MS) of the volatile components, such as metabolites and catabolites, of the sample in order to identify a graphic plot characteristic of a specific bacterial class.
申请公布号 US2016002696(A1) 申请公布日期 2016.01.07
申请号 US201414769436 申请日期 2014.02.20
申请人 ALIFAX HOLDING SPA 发明人 Galiano Paolo
分类号 C12Q1/04;G01N33/497 主分类号 C12Q1/04
代理机构 代理人
主权项 1. Method to identify bacterial classes in a biological sample, in particular a urine sample, wherein said method provides to sow the biological sample in a culture medium or broth and also provides to carry out the analysis by means of Gas Chromatography-Mass Spectrometry (GC/MS) of the volatile components, such as metabolites and catabolites, of said biological sample in order to identify a graphic plot characteristic of a specific bacterial class, characterized in that the analysis using Gas Chromotography-Mass Spectometry provides to identify the presence of metabolic markers and catabolic markers for each bacterial class, and to construct, by identifying said markers, a specific metabolomic profile and a specific catabolomic profile relating to each bacterial species to be identified, and in that the identification of the specific bacterial class present in the biological sample is obtained by comparing the specific plot obtained by the GC/MS analysis with respect to a plot relating to the specific culture medium without the biological sample.
地址 Polverara IT