发明名称 Therapeutic Compounds and Uses Thereof
摘要 Described herein are compounds of Formula (I) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Methods of using the compounds or pharmaceutical compositions thereof for treating diseases are also provided.;
申请公布号 US2016002254(A1) 申请公布日期 2016.01.07
申请号 US201414768038 申请日期 2014.02.18
申请人 KALA PHARMACEUTICALS, INC. 发明人 Ong Winston Zapanta;Nowak Pawel Wojciech;Askew Ben C
分类号 C07D491/107;C07D405/12;C07D405/14;C07D413/14 主分类号 C07D491/107
代理机构 代理人
主权项 1. A compound of Formula (I):or a pharmaceutically acceptable salt thereof,wherein: R1 is hydrogen or optionally substituted C1-6 alkyl; R2 is heterocyclyl; X is a bond, —O—, or —C(═O)—; each instance of R3 is independently selected from the group consisting of hydrogen, F, Cl , Br, I, CN, and OH; Y is CH or N; Z is optionally substituted aliphatic, optionally substituted heterocyclylalkyl, optionally substituted aryl, or optionally substituted heteroaryl; m is independently 0, 1, 2, 3, or 4; and n is independently 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10.
地址 Waltham MA US