SYSTEM FOR PRODUCING TISSUE-ENGINEERED MATERIAL

摘要

A system for producing a tissue-engineered material includes a hollow member and a mechanical stimulating unit. The hollow member is adapted to be implanted in a peritoneal cavity, and is to be positioned in the peritoneal cavity in a manner that a part of the hollow member contacts an inner wall surface of the peritoneal cavity for enabling formation of a biological tissue that encapsulates the hollow member. The mechanical stimulation unit is coupled to the hollow member and configured to provide a periodic mechanical stimulus to the biological tissue by periodically causing the hollow member to expand and contract. A method for producing the aforesaid tissue-engineered material is also disclosed.

主权项

1. A system for producing a tissue-engineered material in a peritoneal cavity of a living subject, said system comprising:
a hollow member adapted to be implanted in the peritoneal cavity, wherein said hollow member is made of a biocompatible and fluid-impermeable material that is expansible and contractible and is to be positioned in the peritoneal cavity in a manner that a part of said hollow member contacts an inner wall surface of the peritoneal cavity for enabling formation of a biological tissue that encapsulates said hollow member; and a mechanical stimulation unit coupled to said hollow member and configured to provide, during a stimulation session, a periodic mechanical stimulus to the biological tissue being formed on said hollow member by periodically introducing a fluid to flow into and out of said hollow member to cause said hollow member to expand and contract accordingly.