| 发明名称 |
Probiotic Strains for Treating and/or Preventing Diarrhea |
| 摘要 |
The present invention relates to a method of selecting or identifying probiotic strains capable of acting on the absorption of water in the colon, and use thereof as medicinal products in the treatment and/or prevention of diarrhea. The invention relates in particular to the strain of Bacillus subtilis CU1 for use in the treatment and/or prevention of diarrhea. |
| 申请公布号 |
US2016000840(A1) |
申请公布日期 |
2016.01.07 |
| 申请号 |
US201314649763 |
申请日期 |
2013.12.12 |
| 申请人 |
LESAFFRE ET COMPAGNIE ;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE INRA ;ECOLE NATIONALE SUPERIEURE DES SCIENCES AGRONOMIQUES DE BORDEAUX AQUITAINE (BORDEAUX |
发明人 |
KHUONG HUU Marie;FIORAMONTI Jean;URDACI Maria |
| 分类号 |
A61K35/742;G01N33/68;C12R1/125 |
主分类号 |
A61K35/742 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of selecting a probiotic strain for treating and/or preventing diarrhea, said method comprising steps of:
measuring the effect of at least one test strain on the expression of at least one transporter involved in the secretion of water in the colon or of at least one transporter involved in the absorption of water in the colon, and selecting at least one strain that induces a decrease in the expression of at least one transporter involved in the secretion of water in the colon and/or an increase in the expression of at least one transporter involved in the absorption of water in the colon. |
| 地址 |
Paris FR |
