发明名称 |
SELECTIVE NUCLEIC ACID SEPARATION |
摘要 |
Nucleic acids in non-rare cells in a sample containing non-rare cells and rare cells are selectively released from the non-rare cells. The sample is combined with an aqueous medium, and the combination is held for a period of time and at a temperature for selectively releasing nucleic acids from the non-rare cells but not from the rare cells. The sample is subjected to filtration to separate rare cells from non-rare cells. Rare cells with intact nucleic acids are separated from non-rare cells and nucleic acids from the non-rare cells. Nucleic acids from the rare cells are subjected to one or more identification techniques either with or without extraction of nucleic acids from the rare cells. |
申请公布号 |
WO2016004308(A1) |
申请公布日期 |
2016.01.07 |
申请号 |
WO2015US38990 |
申请日期 |
2015.07.02 |
申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS INC. |
发明人 |
PUGIA, MICHAEL;PHILIP, JULIA;MARFURT, KAREN |
分类号 |
B01D35/18;C07B63/00;C12N5/07;G01N33/483 |
主分类号 |
B01D35/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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