发明名称 DRUG SELECTION FOR GASTRIC CANCER THERAPY USING ANTIBODY-BASED ARRAYS
摘要 PROBLEM TO BE SOLVED: To provide methods for selecting a suitable anticancer therapy, and methods for identifying and predicting responses for the treatment of gastric cancer.SOLUTION: A method for selecting a suitable anticancer drug for the treatment of gastric cancer comprises: (a) determining the expression level and/or activation level of one or more analytes selected from the group consisting of HER1, HER2, p95HER2, HER3, c-Met, IGF1R, cKit, PI3K, Shc, Akt, p70S6K, VEGFR, PDGFR and combinations thereof in a cellular extract produced from an isolated cancer cell; and (b) selecting a suitable anticancer drug for the treatment of gastric cancer on the basis of the expression level and/or activation level of the one or more analytes determined in step (a).
申请公布号 JP2016001187(A) 申请公布日期 2016.01.07
申请号 JP20150159663 申请日期 2015.08.12
申请人 NESTEC SA 发明人 SINGH SHARAT;KIM PHILLIP;LIU XINJUN;BELEN YBARRONDO
分类号 G01N33/574;G01N33/50;G01N33/542;G01N33/68;G01N37/00 主分类号 G01N33/574
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