METHOD FOR THE QUALIFICATION OF PREPARATIONS OF PENTOSAN POLYSULFATE, RAW MATERIALS AND PRODUCTION PROCESSES THEREOF

摘要

A method for the qualification and selection of manufacturing processes, raw materials, intermediates and batch production of pentosan polysulfate based on the identification of acetylated monosaccharide units, including units of xylose substituted with 4-O-methyl-glucuronic which also lead the acetyl group, as structural characterizing units, is disclosed.

主权项

1) A method for the preparation of polysaccharides of formula wherein R is H or SO3Na G is H, SO3Na or acetyl comprising at least one identification or quantification step of the xylose units substituted with 4-O-methyl-glucuronic acid and acetylated (G=acetyl).