METHODS OF PURIFYING ANTI-INTERLEUKIN-13 ANTIBODIES

摘要

The invention relates to a pharmaceutical composition comprising an interleukin-13 antibody, more particularly a monoclonal interleukin-13 antibody, especially a human interleukin-13 monoclonal antibody, to a process for purifying said antibody and to the use of said composition in treating interleukin-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, chronic obstructive pulmonary disease, scleroderma, inflammatory bowel disease and Hodgkin's lymphoma, particularly asthma.

主权项

1. A pharmaceutical composition comprising an IL-13 antibody and between 10 and 200 mM sodium chloride, between 0.001 and 0.1% (w/w) Polysorbate 80, and between 1 and 100 mM sodium acetate, at a pH between 5.2 to 5.7.