| 发明名称 |
LIGAND BINDING MOLECULES AND USES THEREOF |
| 摘要 |
The present invention is directed to ligand binding molecules and uses thereof to modulate angiogenesis and/or lymphangiogenesis. |
| 申请公布号 |
US2016002612(A1) |
申请公布日期 |
2016.01.07 |
| 申请号 |
US201414768701 |
申请日期 |
2014.02.13 |
| 申请人 |
VEGENICS PTY LIMITED |
发明人 |
Gerometta Michael;Adams Timothy |
| 分类号 |
C12N9/12;A61K39/395;A61K38/45;A61K45/06;C07K16/00 |
主分类号 |
C12N9/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A purified or isolated ligand binding polypeptide comprising an amino acid sequence having at least 95% identity to the sequence of amino acids defined by positions 47-115 of SEQ ID NO: 2, with the proviso that positions of the polypeptide corresponding to positions 104-106 of SEQ ID NO: 2 are not identical to N-X-S or N-X-T,
wherein the polypeptide binds to at least one ligand polypeptide selected from human VEGF-C, VEGF-D, and PIGF. |
| 地址 |
Victoria AU |
