METHOD FOR DETERMINING FORMULATION ORIENTATION OF ASYMMETRIC MULTI-LAYERED OSMOTIC TABLETS

摘要

The present invention relates to a method for preparing asymmetric multi-layered osmotic tablets using rapid and accurate determination of the orientation of tablets with respect to different internal formulation layers proximate to the opposite curved surfaces. In particular, the invention relates to detect degree of curvature using an image recognition system and drill the desired surface using a laser beam.

主权项

1. A method of preparing a multi-layered osmotic tablet having a push end and a dispensing end for laser drilling of a delivery port in the dispensing end, the method comprising the steps of:
detecting an orientation of the tablet by detecting an angle of the curved surface on a side of the tablet corresponding to one or another formulation layer depending on the formulation orientation of the tablet, wherein both the ends have different degrees of curvature; conveying signal to a laser gun regarding orientation of the dispensing end; passing the tablet through a conveyor belt; and drilling the desired surface using a laser beam.