METHODS FOR DIAGNOSING AND TREATING CD1D RESTRICTED GAMMA/DELTA T CELL LYMPHOMAS

摘要

The present invention relates to methods for diagnosing and treating CD1d-restricted gamma/delta T cell lymphomas. In particular, the present invention relates to a method for diagnosing a T cell lymphoma as a CD1d-restricted gamma/delta T cell lymphoma in a patient in need thereof comprising i) detecting the presence of CD1d restricted gamma/delta T lymphoma cells in a cell lymphoma sample obtained from the patient and ii) concluding that the T cell lymphoma is a CD1d-restricted gamma/delta T cell lymphoma when the presence of CD Id restricted gamma/delta T cells is detected in the sample. The present invention also relates to a method for treating a CD1d-restricted gamma/delta T cell lymphoma as diagnosed by the diagnostic method of present invention comprising administering the patient with a therapeutically effective amount of a CD1d antagonist.