TIME-RESOLVED LASER-INDUCED FLUORESCENCE SPECTROSCOPY SYSTEMS AND USES THEREOF

摘要

The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.

主权项

1. A system for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation comprising:
(i) a laser source connected to a biological sample via excitation fibers (ExF), wherein the laser is configured to radiate the biological sample with a laser pulse at a predetermined wavelength to cause the biological to produce a responsive fluorescence signal; (ii) collection fibers (CF), wherein the CF collect the fluorescence signal from the sample, and relays the signal to a demultiplexer; (iii) a demultiplexer comprising wavelength splitting filters so as to split the signal from the CF at pre-determined wavelengths to obtain spectral bands; and (iv) an optical delay device.