发明名称 |
METHOD FOR THE TARGETED KILLING OF CELLS BY NUCLEOTIDE MOLECULES DIRECTED FOR MRNA BINDING, AND ALSO NUCLEOTIDE MOLECULES AND APPLICATION KIT FOR SUCH A USE |
摘要 |
Nucleotide molecules are used for the targeted killing of cells, which bind with a nucleotide sequence to a single region of the mRNA which, according to sequencing analyses, is statistically very rarely subject to a mutation and, thus, also in case of increased mutation rates in the whole genome, reliably kills the cell without further mRNA binding or other influence on the cell being necessary. |
申请公布号 |
EP2961842(A2) |
申请公布日期 |
2016.01.06 |
申请号 |
EP20140711693 |
申请日期 |
2014.02.26 |
申请人 |
FRIEDRICH-SCHILLER-UNIVERSITÄT JENA |
发明人 |
LUDWIG, MIRKO;PÖHLMANN, TOBIAS;GÜNTHER, ROLF;REICHE, JULIANE |
分类号 |
C12N15/11;A61K31/7088;C12N15/113 |
主分类号 |
C12N15/11 |
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