发明名称 |
METHODS FOR TREATING GI SYNDROME AND GRAFT VERSUS HOST DISEASE |
摘要 |
<p>It has been discovered that administering therapeutically effective amounts of an antibiotic that kills Gram-negative bacteria, together with an anti-ceramide antibody or anti-ceramide mimetic, treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTL)-induced killing and/or by damage to endothelial microvasculature, including Radiation GI syndrome, CGvHD disease, inflammatory diseases and autoimmune diseases.</p> |
申请公布号 |
EP2854850(A4) |
申请公布日期 |
2016.01.06 |
申请号 |
EP20130793069 |
申请日期 |
2013.05.28 |
申请人 |
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
KOLESNICK, RICHARD;ROTOLO, JIMMY |
分类号 |
A61K39/395;A61K31/4709;A61K31/496;A61K31/55;A61K38/00;A61K45/06;A61P1/00;A61P1/04;A61P37/02;A61P37/06;C07K16/18;C07K16/44 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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