摘要 |
<p>The present invention relates to pyridines or pyrazines that inhibit kinases. In particular the compounds of formula 1 inhibit FMS (CSF-1R), c-KIT, PDGFR.beta., FLT3, KDR, SRC, EphA2, EphA3, EphA8, FLT1, FLT4, HCK, LCK, PTK5 (FRK) or RET. (see formula 1)</p> |