发明名称 |
Polymerase |
摘要 |
An engineered DNA polymerase characterised in that the polymerase exhibits an enhanced ability to process nucleic acid in the presence of environmental and biological inhibitors compared to wild type DNA polymerase. |
申请公布号 |
US9228179(B2) |
申请公布日期 |
2016.01.05 |
申请号 |
US201313769655 |
申请日期 |
2013.02.18 |
申请人 |
MEDICAL RESEARCH COUNCIL |
发明人 |
Holliger Philipp;D'Abbadie Marc;Baar Claudia |
分类号 |
C12N9/12 |
主分类号 |
C12N9/12 |
代理机构 |
Marshall, Gerstein & Borun LLP |
代理人 |
Marshall, Gerstein & Borun LLP |
主权项 |
1. An engineered polymerase consisting of the amino acid sequence of SEQ ID NO: 2 and exhibiting at least a two-fold enhanced ability compared to the ability of the wild type Thermus aquaticus polymerase to process nucleic acid in the presence of humic acid at a concentration between 5 and 20%. |
地址 |
Swindon GB |