发明名称 |
Oligomer modified diaromatic substituted compounds |
摘要 |
Disclosed are compounds comprising diaromatic substituted compound residues, namely the anti-viral (anti-HIV) drug delavirdine, covalently attached via a linkage to water-soluble, non-peptidic oligomers, specifically to poly(ethylene glycol) (PEG) oligomers. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over non-oligomer modified diaromatic substituted compounds. |
申请公布号 |
US9226970(B2) |
申请公布日期 |
2016.01.05 |
申请号 |
US201113580580 |
申请日期 |
2011.02.22 |
申请人 |
Nektar Therapeutics |
发明人 |
Riggs-Sauthier Jennifer;Deng Bo-Liang |
分类号 |
A61K31/497;A61K47/48 |
主分类号 |
A61K31/497 |
代理机构 |
|
代理人 |
Wilson Mark A. |
主权项 |
1. A compound having the following structure,wherein n is an integer between 1 and 30, inclusive, and pharmaceutical salts thereof. |
地址 |
San Francisco CA US |