Personal care and medicinal products incorporating bound organosulfur groups

摘要

Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-microbial, anti-oxidant, anti-inflammatory, and anti-aging properties and are suitable for use without a prescription. The products utilize a biomembrane permeable organosulfur compound that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to oxidants and antioxidants inside and outside of cells. Example products include an anti-microbial toothpaste with anti-plaque properties, an anti-inflammatory skin lotion with antioxidant, antimicrobial, and deodorant properties, and an anti-toxin skin lotion with anti-arsenicosis properties.

主权项

1. A method of therapeutic treatment of a host suffering from a skin condition which can benefit from treatment with a membrane permeable antioxidant, said condition selected from the group consisting of:
(a) sunburn, (b) dermatitis due to poison oak or poison ivy, (c) free radical damage, and (d) arsenicosis said method comprising topically applying to skin of said host a composition comprising a membrane permeable antioxidant and a dermatologically acceptable carrier suitable for topical application to the skin, wherein the membrane permeable antioxidant is a therapeutically effective amount of an allium related compound selected from the group consisting of allyl mercaptan, n-propylmercaptan, diallyl disulfide,di-n-propyl disulfide, n-propyl allyl disulfide and combinations thereof, and wherein the allium related compound is sufficiently bound to the carrier to be non-volatile, but said binding is readily broken upon application to the skin.