| 发明名称 | Specific A1AT monoclonal antibodies for detection of endometriosis | ||
| 摘要 | Provided herein are monoclonal antibodies with a high binding affinity to isoforms of alpha 1-antitrypsin (A1AT), hybridoma cells producing the same, and their uses in diagnosing and/or detecting endometriosis from a serum sample of a subject suspicious of having endometriosis or a subject under health examination. | ||
| 申请公布号 | US9229012(B2) | 申请公布日期 | 2016.01.05 |
| 申请号 | US201313942529 | 申请日期 | 2013.07.15 |
| 申请人 | Taipei Medical University;Academia Sinica | 发明人 | Yang Wei-Chung;Wang Hwei-Jiung;Chen Shui-Tsung;Lu Ken-Fen;Peng Ming-Chi |
| 分类号 | G01N33/53;G01N33/68;C07K16/18;C07K16/38 | 主分类号 | G01N33/53 |
| 代理机构 | Muncy, Geissler, Olds & Lowe, P.C. | 代理人 | Muncy, Geissler, Olds & Lowe, P.C. |
| 主权项 | 1. A monoclonal antibody which specifically binds to an epitope of an isoform of alpha 1-antitrypsin (A1AT) having a molecular weight of about 72 kDa or 58 kDa in a biological sample of a subject, wherein the epitope consists of an amino acid sequence of SEQ ID NO: 3. | ||
| 地址 | Taipei TW | ||