发明名称 |
Methods for treating microbial infection |
摘要 |
A method for treating a microbial infection or an abscessed tissue in a subject includes administering to the subject an effective amount of a metal ion chelator. In some embodiments, the metal ion chelator can be a protein, such as a calprotectin heterodimer. In some embodiments, the metal ion chelator is a calprotectin heterodimer including an S100A8 polypeptide and an S100A9 polypeptide. |
申请公布号 |
US9226947(B1) |
申请公布日期 |
2016.01.05 |
申请号 |
US201414512867 |
申请日期 |
2014.10.13 |
申请人 |
Vanderbilt University |
发明人 |
Skaar Eric P.;Corbin Brian |
分类号 |
C07K14/00;A61K38/17 |
主分类号 |
C07K14/00 |
代理机构 |
Stites & Harbison PLLC |
代理人 |
Stites & Harbison PLLC ;Decker Mandy Wilson |
主权项 |
1. A kit, comprising: a vial containing a manganese ion chelator that is a protein, wherein the manganese ion chelator is Ca2+-bound, or wherein the kit further comprises a vial containing a Ca2+-containing buffer. |
地址 |
Nashville TN US |