发明名称 Methods for treating microbial infection
摘要 A method for treating a microbial infection or an abscessed tissue in a subject includes administering to the subject an effective amount of a metal ion chelator. In some embodiments, the metal ion chelator can be a protein, such as a calprotectin heterodimer. In some embodiments, the metal ion chelator is a calprotectin heterodimer including an S100A8 polypeptide and an S100A9 polypeptide.
申请公布号 US9226947(B1) 申请公布日期 2016.01.05
申请号 US201414512867 申请日期 2014.10.13
申请人 Vanderbilt University 发明人 Skaar Eric P.;Corbin Brian
分类号 C07K14/00;A61K38/17 主分类号 C07K14/00
代理机构 Stites & Harbison PLLC 代理人 Stites & Harbison PLLC ;Decker Mandy Wilson
主权项 1. A kit, comprising: a vial containing a manganese ion chelator that is a protein, wherein the manganese ion chelator is Ca2+-bound, or wherein the kit further comprises a vial containing a Ca2+-containing buffer.
地址 Nashville TN US