A COMPOSITE FOR PREVENT CHEMOKINE-INDUCED DISEASE CONTROLLING CHEMOKINE COMPRISING RED GINSENG EXTRACT

摘要

The present invention relates to a red ginseng extract for preventing or treating atopic dermatitis by adjusting chemokine. In particular, the present invention relates to a red ginseng extract for preventing or treating atopic dermatitis by adjusting interleukin (IL)-8, thymus and activation regulated chemokine (TARC), macrophage-derived chemokine (MDC), and matrix metallopeptidase (MMP)-9. The red ginseng extract for preventing or treating atopic dermatitis by adjusting chemokine according to the present invention inhibits activities of mitogen-activated protein kinases (MAPKs) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) in an animal model whose skin disease induced by 1-fluoro-2,4-dinitrobenzene (DNFB), and controls a morbidity caused by a systemic anaphylactic shock.